View abstract. Basic Clin.Pharmacol.Toxicol. Sahebkar A, Serban C, Ursoniu S, Banach M. Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials. 12-6-2006;108(3):385-394. These include: The intake of too much garlic can cause adverse effects. J Tradit.Chin Med 2000;20(4):243-246. Cancer Epidemiol.Biomarkers Prev. However, bad breath can be embarrassing. Bleumink, E. and Nater, J. P. Contact dermatitis to garlic; crossreactivity between garlic, onion and tulip. Herbal Medicine Expanded Commission E Monographs. J Nutr. View abstract. J Ayub.Med Coll.Abbottabad. 2006;13(3):141-146. Anibarro B, Fontela JL, De La Hoz F. Occupational asthma induced by garlic dust. Neurosurgery 1990;27(4):659. View abstract. 2007;14(7-8):447-451. View abstract. Phytother.Res. View abstract. Fedder, S. L. Spinal epidural hematoma and garlic ingestion. Prostaglandins Leukot Essent Fatty Acids 1996;54(3):183-186. Steiner M, Li W. Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions. 2011;24(4):565-570. 2011 - 2023 IncNut Stylecraze Private Limited. View abstract. 2007;25(4):164-168. View abstract. Dalmartello M, Turati F, Zhang ZF, et al. While garlics effects are comparable to standard blood-pressure drugs, it has been found that people who have inadequate levels of vitamin B may not experience this benefit. Inflamm.Allergy Drug Targets. Med Lett Drugs Ther 1997;39:9-10. Experientia 2-15-1996;52(2):115-120. View abstract. View abstract. ", P.F. Ip C, Lisk DJ. Ernst E. Can allium vegetables prevent cancer? Fitoterapia 2001;72(5):524-531. J Am Acad Dermatol 2000;43:829-32. Sitprija, S., Plengvidhya, C., Kangkaya, V., Bhuvapanich, S., and Tunkayoon, M. Garlic and diabetes mellitus phase II clinical trial. Economic and Medicinal Research. Garlic is one of those foods that people love to eat Cancer Epidemiol Biomarkers Prev. Chin Med J (Engl.) Prostaglandins Leukot Essent Fatty Acids 2000;62:55-73. Coppi, A., Cabinian, M., Mirelman, D., and Sinnis, P. Antimalarial activity of allicin, a biologically active compound from garlic cloves. Oncology 1989;46(4):277-280. The impact of garlic on lipid parameters: a systematic review and meta-analysis. View abstract. J Nutr 2001;131(3s):1027S-1031S. View abstract. Mader FH. Recent studies with a standardized dry garlic powder substance]. Atherosclerosis 1981;39:447-52. Ashraf, M. Z., Hussain, M. E., and Fahim, M. Endothelium mediated vasorelaxant response of garlic in isolated rat aorta: role of nitric oxide. 2003;51(3):593-597. View abstract. [Two cases of eosinophilic gastroenteritis whose causative allergens are usefully diagnosed by patch test]. Koushki M, Amiri-Dashatan N, Pourfarjam Y, Doustimotlagh AH. Dtsch Apoth Ztg 1989;129(suppl 15):1-25. A., Karabasova, IaA, Liutova, L. I., Povorinskaia, T. E., and Orekhov, A. N. [Use of allikor for the normalization of fibrinolysis and hemostasis in patients with chronic cerebrovascular diseases]. View abstract. Phytother.Res. Cronin E. Dermatitis of the hands in caterers. Can I drink water after eating garlic on an empty stomach? Does garlic induce labor in pregnant women? Which Is Healthier, Raw or Cooked Garlic? Nutr Cancer. Kheirmandparizi M, Keshavarz P, Nowrouzi-Sohrabi P, et al. View abstract. Applies to garlic: oral capsule, oral tablet. A., Krzhivitskii, P. I., Semiglazov, V. F., Aleksandrov, V. A., Sobenin, N. A., and Orekhov, A. N. [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease]. Other studies have also shown that allicin can help inhibit the growth of the bacteria methicillin-resistant Staphylococcus aureus (MRSA). J Ethnopharmacol. Allium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project. View abstract. 2003;55(2):199-202. Diabetes Obes.Metab 2011;13(4):289-301. View abstract. 2012;36(5):439-444. View abstract. These side effects are often worse with raw garlic. View abstract. View abstract. Rose KD, Croissant PD, Parliament CF, Levin MB. Lei, Y. P., Chen, H. W., Sheen, L. Y., and Lii, C. K. Diallyl disulfide and diallyl trisulfide suppress oxidized LDL-induced vascular cell adhesion molecule and E-selectin expression through protein kinase A- and B-dependent signaling pathways. One of the many other side effects of garlic during pregnancy is that it can also decrease the absorption capacity of iodine and cause hypothyroidism. 1999;141(2):391-392. Duncan A, Mills J. Efendy JL, Simmons DL, Campbell GR, Campbell JH. J Spec Oper Med. View abstract. 2003;133(7):2171-2175. WebThe Effects of Eating Too Much Garlic on Digestion. Tanamai, J., Veeramanomai, S., and Indrakosas, N. The efficacy of cholesterol-lowering action and side effects of garlic enteric coated tablets in man. View abstract. Roussos AP, Hirsch AR. Evans V. Herbs and the brain: friend or foe? Phytother.Res. Dunstan, J. Cancer 6-1-1993;71(11):3575-3581. Beneficial effect of aged garlic extract on periodontitis: a randomized controlled double-blind clinical study. View abstract. Nagae, S., Ushijima, M., Hatono, S., Imai, J., Kasuga, S., Matsuura, H., Itakura, Y., and Higashi, Y. Pharmacokinetics of the garlic compound S-allylcysteine. Pai, S. T. and Platt, M. W. Antifungal effects of Allium sativum (garlic) extract against the Aspergillus species involved in otomycosis. On the effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolaemia. View abstract. Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation. Arzneimittelforschung 1993;43:119-22. Gravas S, Tzortzis V Rountas C Melekos MD. View abstract. Arztliche Forschung 1988;3:3-8. But if you are already on medications for high blood pressure, it may lead to hypotension (low blood pressure). BMC.Pharmacol 12-20-2003;3(1):16. Sumioka I, Matsura T, Yamada K. Therapeutic effect of S-allylmercaptocysteine on acetaminophen-induced liver injury in mice. Deutsche Apotheker Zeitung 1989;129(28 suppl 15):16-17. Further research is needed to understand the effects on humans. A., and Williams, M. A systematic review of the effectiveness of garlic as an anti-hyperlipidemic agent. Allium vegetable consumption, garlic supplement intake, and female breast carcinoma incidence. It can cause side effects such as bad breath, heartburn, gas, and diarrhea. Wiad.Lek. Instead, eat what you can tolerate and avoid garlic supplements, as they may not have the effect that you are hoping for. Petry, J. J. Garlic and postoperative bleeding. Garlic may interact with medications such as blood thinners. View abstract. Maternal diet alters the sensory qualities of human milk and the nursling's behavior. Am J Clin Nutr 1977;30(9):1380-1381. View abstract. The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis. Eating too much garlic may cause issues like bloating, gas, and heartburn. Qidwai, W., Qureshi, R., Hasan, S. N., and Azam, S. I. Vegetables, fruit, and colon cancer in the Iowa Women's Health Study. View abstract. Hughes BG, Murray BK, North JA, and et al. Effect of topical garlic on wound healing and scarring: A clinical trial. Baruchin, A. M., Sagi, A., Yoffe, B., and Ronen, M. Garlic burns. View abstract. The results suggest that caution must be exercised before using garlic and related products as they may have undesirable effects on gastric health. View abstract. Ahmad, M. S., Pischetsrieder, M., and Ahmed, N. Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts. Kendler, B. S. Garlic (Allium sativum) and onion (Allium cepa): a review of their relationship to cardiovascular disease. View abstract. 1997;66(2):398-405. 2011;315(2):87-93. Anthony, J. P., Fyfe, L., and Smith, H. Plant active components - a resource for antiparasitic agents? 2017 Jan;28(1):4-15. He has been in the digital media field for over eight years. View abstract. In fact, eating too much garlic can lead to adverse effects. Woodbury A, Sniecinski R. Garlic-induced surgical bleeding: How much is too much? J Nutr 2001;131(3s):1106S-1108S. A., Pryanishnikov, V. V., Kunnova, L. M., Rabinovich, Y. View abstract. View abstract. Mukherjee, M., Das, A. S., Mitra, S., and Mitra, C. Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) View abstract. Trop.Biomed. Though it doesnt directly cause a migraine headache, it activates the process responsible for it. Apitz-Castro, R., Escalante, J., Vargas, R., and Jain, M. K. Ajoene, the antiplatelet principle of garlic, synergistically potentiates the antiaggregatory action of prostacyclin, forskolin, indomethacin and dypiridamole on human platelets. Treatment of venous ulcers with the herbal-based ointment Herbadermal(R): a prospective non-randomized pilot study. J Ethnopharmacol 2001;76:229-32.. View abstract. Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans. Hiltunen, R., Josling, P. D., and James, M. H. Preventing airborne infection with an intranasal cellulose powder formulation (Nasaleze travel). View abstract. Hirsch, K., Danilenko, M., Giat, J., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Levy, J., and Sharoni, Y. Karabacak E, Aydin E, Kutlu A, Dogan B. Its health action comes from the enzymes and unique compounds that it contains. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Garcia-Anoveros, J. and Nagata, K. TRPA1. Effect of garlic on total serum cholesterol. Cook-Mozaffari, P. J., Azordegan, F., Day, N. E., Ressicaud, A., Sabai, C., and Aramesh, B. Oesophageal cancer studies in the Caspian Littoral of Iran: results of a case-control study. Garlic might also increase the risk of bleeding and cause allergic reactions in some people. Further research is needed to understand the effects on humans. Cochrane.Database.Syst.Rev. Garlic may trigger diarrhea as it may cause gas (7). View abstract. Nahas, R. and Balla, A. Complementary and alternative medicine for prevention and treatment of the common cold. View abstract. Qureshi AA, Din ZZ, Abuirmeileh N, et al. Infographic: Ingredient Spotlight: Garlic. Nikolic, V., Stankovic, M., Nikolic, Lj, and Cvetkovic, D. Mechanism and kinetics of synthesis of allicin. Hussain, S. P., Jannu, L. N., and Rao, A. R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. Planta Med 1992;58:8-13. Superko HR, Krauss RM. Jpn.J Cancer Res 1999;90(6):614-621. Sabitha, P., Adhikari, P. M., Shenoy, S. M., Kamath, A., John, R., Prabhu, M. V., Mohammed, S., Baliga, S., and Padmaja, U. Efficacy of garlic paste in oral candidiasis. J Ocul.Pharmacol.Ther 1999;15(1):9-17. Sunter WH. View abstract. A comparative study on the effectiveness of garlic with clofibrate in the treatment of hyperlipidemia. Tong XF and Cheng HS. 16 Mar. Hoshino, T et al. Int J Clin Pract. Mitchell, J. C. Contact sensitivity to garlic (Allium). Ann Pharmacother 2000;34(12):1478-1482. View abstract. Journal of Medical Council of Islamic Republic of Iran (J MED COUNC ISLAMIC REPUB IRAN) 2005;23(3):319. J Med Food 2009;12(3):542-551. Gao YT, McLaughlin JK, and Gridley G. Risk factors for esophageal cancer in Shanghai, China. View abstract. Exp Ther Med. doi: 10.1136/bmj.l5016. Ince DI, Sonmez GT, and Ince ML. Pak J Pharm Sci 2013;26(5):859-63. Sheela CG, Kumud K, Augusti KT. View abstract. J Am Coll Nutr 2001;20(3):225-231. View abstract. Spices like garlic get excreted through your sweat as well as your digestive system. Garlic oil has also been found to be protective against cardiomyopathy, a type of chronic heart disease that is the leading cause of death among diabetes patients. 1987;8(2):79-85. Kabasakal, L., Sehirli, O., Cetinel, S., Cikler, E., Gedik, N., and Sener, G. Protective effect of aqueous garlic extract against renal ischemia/reperfusion injury in rats. 2005;35(2):99-100. Ried K, Toben C, Fakler P. Effect of garlic on serum lipids: an updated meta-analysis. View abstract. View abstract. Clin Chim.Acta 1999;285(1-2):21-33. View abstract. Garlic may lower blood pressure (10). Arzliche Forschung 1988;3:1-8. 2012;29(2):e680-e684. Eur.J Obstet.Gynecol.Reprod.Biol. Protective effect of aged garlic extract on the small intestinal damage of rats induced by methotrexate administration. Am.J Clin Nutr. Int.J.Clin.Pharmacol.Ther. 1997;8(1):41-44. in an ovariectomized rat model of osteoporosis. Bhuvaneswari, V., Abraham, S. K., and Nagini, S. Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis. Dizziness or weakness. Siegel G. Long-term effect of garlic in preventing arteriosclerosis - results of two controlled clinical trials. J Ethnopharmacol. Contact Dermatitis 1991;24:193-6. Can J Physiol Pharmacol. Nishino, H., Iwashima, A., Itakura, Y., Matsuura, H., and Fuwa, T. Antitumor-promoting activity of garlic extracts. Zhang S, Gu Y, Wang L, et al. View abstract. J Nutr. 2006;136(3 Suppl):821S-826S. Phytomedicine 1999;6:125-31. Avoid garlic if you're already taking an anticoagulant, such as Coumadin (warfarin) or Heparin, because the blood-thinning action of the medication may be increased. 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